Bronchitis - Tamiflu for the Treatment of Influenza
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Tamiflu for the Treatment of Influenza

About Tamiflu - It's Manufacturer

Tamiflu (Oseltamivir) is an oral antiviral treatment (not a vaccine) for influenza, and belongs to a class of drugs called neuraminidase inhibitors (NAI). It prevents the virus from spreading inside the body and works well against all strains.

Roche, the manufacturer of Tamiflu since 1996, acquired the worldwide rights to develop and market the drug from Gilead Sciences, Foster City, California.


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Tamiflu can be used both for prevention and treatment of influenza. An oral medication, it is a convenient 75mg capsule which affects all key sites in the body where the virus multiplies. The dose for the adult treatment of influenza is a 75mg capsule, taken twice daily for five days. A pack of Tamiflu contains a full treatment course of 10 capsules.

Treatment must commence within 48 hours of the onset of symptoms for full efficacy. For post exposure prophylaxis the dosage is one 75mg capsule daily for up to 6 weeks.

Tamiflu is proven to be effective in adults and in children one year and older.

What is an Influenza Virus?

Influenza is a disease caused by a member of the Orthomyxoviridae. Many features are common with those of the Paramyxovirus infections of the respiratory tract. Influenza, commonly called - the 'flu'- is a serious disease caused by influenza A and B viruses, which usually occurs seasonally in the autumn and winter months. According to the WHO 3-5 million cases of seasonal influenza occur every year.

The influenza virus is classified into three categories: A, B, and C. Type A is the most serious and usually appears every two or three years. Prone to mutation, it regularly produces nonresistant strains; has caused many epidemics; and is also responsible for pandemics, in which entire continents are affected.

Type B influenza virus is the strain responsible for smaller infection outbreaks. Once infected with this virus, the immune system successfully resists this type of virus for many years. This type commonly infects uninfected children aged between 5-14 years.

Type C influenza virus is a very mild strain of the infection, similar to symptoms of a common cold. This can be treated with bed rest and plenty of fluid intake.

How to Treat Influenza Virus

The flu targets your respiratory system (nose, lungs, throat and bronchial tubes). During the flu, a patient exhibits some or all of the following symptoms.



Loss of appetite

Fever

Congestion that turns to a runny nose

Sore throat

Cough that turns productive

 
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Exhaustion and weakness

Muscle aches and pains



It is possible to treat the flu using medication as well as make a rapid recovery using various means like:



Keeping your fluid intake to the optimum - Flu sufferers lose a lot of fluids from having high fevers. Drink plenty of water. Orange juice is good for its vitamin C content, too, and sports drinks like Gatorade help replenish electrolytes.

Proper sleep - Adequate rest also helps in recovery.

Taking a healthy diet - Even though you don't feel like eating, nutrition is an important part of recovery.

Minimal exertion - It is better to stay in bed and recuperate through relaxation..

Keeping the fever in check - Young children often suffer higher fever during the flu.



Toddlers should be attended to by a pediatrician in the event of a high fever that lasts for a day and for adults a doctor should be consulted when the fever exceeds 103 degrees or lasts longer than two days and is accompanied by significant fatigue or any kind of pain. The elderly and those with diabetes, a weakened immune system, cardiovascular disease, pregnancy beyond the first trimester, lung disease or asthma should call their doctor when flu symptoms arrive.

When administered according to its approved dosage (75 mg twice daily for 5 days), Tamiflu delivers a 38 per cent reduction in the severity of symptoms, a 67 per cent reduction in secondary complications such as bronchitis, pneumonia and sinusitis in otherwise healthy individuals and a 37 per cent reduction in the duration of influenza illness. This data were derived from seasonal outbreaks of influenza.

Side Effects of Tamiflu

Possible Tamiflu side effects, although not common, include:



Nausea

Vomiting

Diarrhea

Bronchitis

Stomach pain

Dizziness

Headache



More serious side effects have also sometimes been reported. According to the FDA, there have been reports (mostly from Japan) of patients causing self-injury or experiencing delirium (confusion, hallucinations, speech problems) while using Tamiflu.

 
 
     
 
 





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